ERIC Number: EJ797754
Record Type: Journal
Publication Date: 2008-Sep
Pages: 10
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0009-398X
EISSN: N/A
Objective versus Subjective Assessment of Methylphenidate Response
Manor, Iris; Meidad, Sheera; Zalsman, Gil; Zemishlany, Zvi; Tyano, Sam; Weizman, Abraham
Child Psychiatry and Human Development, v39 n3 p273-282 Sep 2008
Subjective improvement-assessment in attention deficit/hyperactivity disorder (ADHD), following a single dose of methylphenidate (MPH) was compared to performance on the Test-of-Variables-of-Attention (TOVA). Self-perception was assessed with the clinical-global-impression-of-change (CGI-C). Participants included 165 ADHD subjects (M:F ratio 67%:33%) aged 5-18 (11.09 plus or minus 3.43) years. TOVA was administered before and after MPH challenge (0.3 mg/kg). Self-perception CGI-C scores were compared to the TOVA scores. An inverse correlation was found only between CGI-C and the TOVA-Commission-scores (r = -0.326, p less than 0.001). We thus conclude that subjective reports are too unreliable to be used in order to assess MPH benefit in ADHD pediatric populations.
Descriptors: Hyperactivity, Attention Deficit Disorders, Drug Therapy, Metacognition, Measures (Individuals), Comparative Analysis, Correlation, Children
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A