This article presents a short dermatological case presentation involving a 12-year-old white male who has Pityriasis rosea. Pityriasis rosea is an acute, benign, self-limiting disorder that affects males and females equally. It rarely occurs in children younger than 5 years of age but can occur in children as young as 1 year. It is most commonly seen in school age children, adolescents, and young adults. Health history, physical findings on the subject, and differential diagnosis, such as Coxsackie, Pityriasis rosea, Tinea corporis, ECHO virus, Scarlet fever, and Infectious mononucleosis, are given. It is followed by a discussion of the disease or condition and how the school nurse should handle it.