The scourge of emerging parasitic diseases (e.g., urinary schistosomiasis, ascariasis, malaria, chagas disease, leishmaniasis, trachoma, trichiuriasis, taeniasis, dracunculiasis, sleeping sickness, filariasis) causes tremendous pain, suffering, and eventually death in tropical African communities. Patterns of transmission of these emerging parasitic diseases in a cultural setting are regulated by a complete interplay of human factors, including those which act as effective barriers to the spread of diseases. A greater understanding of these factors, particularly regarding some clinical signs, symptoms, or manifestations is necessary to aid in determining what changes if introduced would upset the established culture. Highlighted are some of the cultural human behavioral patterns mitigating against prevention and control measures of diseases as well as discussion of local beliefs and some problematic practices with emerging parasitic diseases. Health education is identified as a major factor in erasing negative beliefs, cultural practices, and behavioral patterns which promote the emergence of parasitic diseases in tropical African communities.