This research presents an analysis of factors predicting job retention, job satisfaction, and job performance of workers with mental retardation. The findings highlight self-determination as a critical skill in predicting the three important employee outcomes. The study examined a hypothesized job retention model and the outcome of the three regression analyses used to test the model. The intent of the study was to develop job retention strategies that could offer rehabilitation and HR professionals a useful structure for understanding and implementing job retention interventions for people with mental retardation. (Contains 4 tables and 5 figures.)