Objective: The author examined whether the type of intimacy (ie, emotional, intellectual, sexual, social, recreational) featured in college students' romantic relationships affects the extent to which a partner's health-related behavior may be influenced by a variety of behavior change appeals. Participants: One hundred and thirteen female and 94 male college students were surveyed. Methods: A questionnaire sought demographic information and included 2 scales to determine intimacy type levels and estimated responses to behavior change appeals. Results: It was determined that emotional and intellectual intimacy had the greatest effects on compliance estimates. The liking strategy was rated as generally most effective, whereas caring fared better in highly intimate relationships, and both threat and responsibility appeals functioned better in relationships featuring lower levels of intimacy. Conclusions: When appropriately qualified as initial findings, the outcomes may suggest routes to successfully inspiring particular health behavior changes, especially among partners in emotionally and intellectually intimate relationships. (Contains 4 tables.)