The author describes the benefits of university-based women entrepreneur centers as an educational and outreach strategy and argues for their establishment and support by universities interested in educating women entrepreneurs and advancing women-owned businesses. Based on extensive research on women business owners and firsthand experience with two such U.S. university-based centers, the author describes their several advantages in meeting the distinctive needs of women as entrepreneurs and learners. Providing examples of and rationales for the effectiveness of these programs, the author also makes a case for their potential economic development benefits for the larger economy and community and contributions to their sponsoring universities.