This study used self-report symptom inventories administered in school classrooms to examine relations among gender, psychological symptoms, stress, and coping in 1,200 low-income African American urban early adolescents. Girls reported more symptoms than boys, accounted for by higher internalizing symptoms. Boys reported more stress than girls, particularly major events, controllable events, exposure to violence, and sexual stressors. Boys in gangs reported greater exposure to sexual stressors than non-gang members. Expressing feelings coping, used more by girls, was related to more symptoms and is posited to be a type of co-rumination. Rumination coping, used as a primary strategy by both boys and girls, was related to higher symptom levels. Risk to low-income African American boys from high violence exposure and sexual stressors, the problematic effect of maladaptive coping strategies for youth exposed to high stress, and how culture and experience are relevant to understanding gender differences in psychological symptoms are discussed. (Contains 4 tables and 2 notes.)