Conducted performance monitoring of at-risk and not-at-risk students in a general biology course for non-science majors, using Marsh's Biomathematical Skills Test (BST), grades, gender, rank, and self-concept and nature of science surveys. Data supported the usefulness of the BST. At-risk students performed less well than not-at-risk students on all examinations and earned more D and F grades. Predicted GPA explained the largest proportion of variance in the BST model. (EV)