This column focuses on evidence-based practice (EBP) within multidisciplinary outpatient settings, but first provides some definitions. Besides EBP (Burns and Hoagwood, 2005; Guyatt and Rennie, 2002), there are also evidence-based medicine (EBM; March et al., 2005), evidence-based service (EBS; Chorpita et al., 2002), and evidence-based treatment (EBT; Kazdin, 2005). The term empirically supported treatment (EST) is often used interchangeably with EBT (Chorpita, 2003). EBM focuses on the practitioner, EBT focuses on the therapy, and EBS focuses on a large system. Yet it is often the multidisciplinary team serving outpatients that is the natural unit of organization in delivering services. From diagnostic processes to how clinicians build alliances with families, which therapies are offered, how medicines are administered and follow-up is tracked, a child mental health team committed to EBP functions differently from how most teams function at present. This conception of implementing EBPs goes beyond any single component, such as importing EBTs or encouraging searches of relevant answerable questions. Together these individual elements reinforce and support each other to create an EBP culture. The task of motivating staff to build an EBP culture is formidable. A shift toward commitment to EBP is difficult to achieve and a long-term project: Most teams are part of a larger system, and system change processes may require a decade or more (Lyons, 2004). (Contains 1 table.)