This dissertation explored the extent to which Information Technology (IT) strategic alignment are impacted by IT governance structures. The study discusses several strategic alignment and IT governance literature that presents a gap in the literature domain. Subsequent studies researched issues surrounding why organizations are not able to align business and IT using previous models. Successive research took the form of case studies and observations that lacked testing of actual theories. The purpose of this study was to explore the extent to which IT strategic alignment is affected by IT governance structures. This literature review evaluates common strategic alignment themes, limitations, methodologies, results and addressed a gap in literature by exploring decision making through organizational IT governance structures that add knowledge to the literature domain of IT strategic alignment and IT governance. The study adapted a non-experimental, correlative quantitative research used to determine the extent to which causal relationships exist for exploring four research questions. The studies population sample came from 4000 business and technology managers and executives of which 300 responded within the response timeframe. The study tested several hypothesis that yielded positive and negative correlations. The study concludes on the statistical correlation between IT strategic alignment and IT governance structural factors affecting organizational goals, objectives and competitive advantage. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]