With the high demand to build the science, technology, engineering, and mathematics (STEM) workforce and the disparity of underrepresented minorities in STEM fields, there have been increased educational efforts to diversify STEM fields. This article describes what works in research collaborations between research-intensive universities (RIUs) and minority-serving institutions (MSIs) for increasing the likelihood of pursuing an advanced degree in science, in particular plant breeding. Using a longitudinal case study design, the research collaboration experience is captured from the perspectives of faculty at research-intensive universities and faculty and students from minority-serving institutions through mixed methods, including surveys, interviews, and site visits. All those involved felt the program was valuable and enhanced the experiences of students at the minority-serving institutions by providing research opportunities; however, the intended goal of developing a future pipeline of students into plant breeding was not met. Despite this, the Triticeae Coordinated Agricultural Project (TCAP) research collaborations with the participating MSIs show some promise and there are lessons to be learned for future efforts.