The Comprehensive Trail Making Test (CTMT) is designed to be used in neuropsychological assessment for the purposes of detecting effects of brain defects and deficits and in tracking progress in rehabilitation. More specific purposes include the detection of frontal lobe deficits, problems with psychomotor speed, visual search and sequencing, attention, and impairments in set-shifting. Trail-making tasks used as measures of brain function did not originate with this particular instrument. The original trail-making instrument, the Trail Making Test, Parts A and B, was developed in 1938 by Partington as a measure of divided attention (see Partington & Leiter, 1949). It has been found to be a very useful measure of brain function; however, it does have its shortcomings. Normative tables for the original are insufficient and not representative of the current U.S. population. It is also thought to be too brief and too general. The CTMT was developed to overcome these limitations. The CTMT is made up of a standardized set of five "visual search and sequencing tasks" that are influenced by attention, concentration, resistance to distraction, and cognitive flexibility. These tasks are referred to as trail making. The test is standardized for use with individuals aged 11 through 74. This article discusses the technical adequacy of CTMT.