Education is a process of adapting to change, and the rate of change is especially rapid in science today. This curriculum in human biology is an alternative to the New York State courses in general and Regents biology, and it has been designed to focus on change from the standpoint of the urban student. It is designed to provide students with experiences which encourage the development of critical thinking and problem solving skills. The laboratory experiments are intended to involve students in both the evaluation and interpretation of data, as well as in the design of their own experiments. The document is divided into nine broad units, with each unit divided into a series of sub-topics. The major topics covered are: (1) Why Do We Study Biology? (2) Of What Are Living Things Made? (3) How Do Our Cells Get the Materials They Need? (4) How Do Our Bodies Carry Out Their Activities? (5) Why Do We Behave the Way We Do? (6) How Can We Prevent and Control Disease? (7) How Do Humans Reproduce? (8) What Determines What We Are? and (9) How Have Living Things Changed? Each page in the guide is divided into four columns: (1) performance objectives; (2) basic understandings; (3) suggested procedures; and (4) enrichment activities. (TW)