There exists an increasingly attractive lure of using virtual reality applications for teaching in all areas of education, but perhaps the largest detriment to its use is the intimidating nature of VR technology for non-technical instructors. What are the challenges to using VR technology for the design and development of VR-based instructional activities, and what are the recommended approaches? This paper addresses the issues regarding identifying the appropriate techniques for integrating VR into traditional instructional design, and the considerations for development for non-technical educators. Recommendations are grounded within our own project involving virtual anesthesia. The discussion considers budgetary limitations, funding, and other factors. (Contains 4 tables and 6 figures.)