This paper will outline answers to the two central questions regarding improving engineering education: (1) What is the full set of knowledge, skills, and attitudes that engineering students should possess as they leave the university, and at what level of proficiency?; and (2) How can we do better at ensuring that students learn these skills? The suggested answers lie within an innovative educational framework, the CDIO (conceive-design-implement-operate) Initiative. This initiative will be described along with the needs it meets, its goals, context, vision and pedagogical foundation. The first question is answered by the CDIO Syllabus and the process for reaching stakeholder consensus on the level of proficiency that students should attain in a given program. The second question is addressed through a best practice framework, which discusses curriculum design, design-implement experiences, teaching and learning, student assessment, program evaluation and faculty competence. Examples are provided of the implementation of best practices within the CDIO program in Aeronautics and Astronautics at the Massachusetts Institute of Technology (MIT).