This study tested the effectiveness of video game use for instruction of factorial designs in a research methods course. Students designed and conducted a mini study, playing "Dance, Dance, Revolution", using video game scores as the dependent variable. A mixed-design analysis of variance revealed a significantly greater increase from pretest to posttest in content knowledge in the Wii activity condition compared to lecture-only and no-content control conditions. Implementing this nontraditional teaching method engaged students and increased knowledge of factorial designs in a research method course. (Contains 1 table, 1 figure and 1 note.)