Society has high expectations for the quality and efficacy of science. Research is grounded in the faithful acquisition of new insights, a process in which results have to be discussed and reproduced before they can be accepted as new knowledge. Because the acquisition of new insights in science is tied to people's social lifestyles as well as the nature and technology that surround them, science cannot be decoupled from everyday life but should be recognized as "science for humanity." If science distances itself from these goals and no longer serves the quest for truth, the relevance of its results becomes questionable, because the whole system of science becomes vulnerable to dishonesty and scientific misconduct. If science is increasingly assigned to institutions or organizations, and not to the actual researchers, then there is a threat that the awareness of the responsibility for research results and their scientific relevance will be lost. This article offers suggestions for safeguarding the integrity and quality of science. ["How Science Can Ensure Integrity and Quality: A Thesis" was translated from German by James Geller.]