The stressful effects of advanced academic training were examined in a comparison of six graduate and professional programs at Vanderbilt University. The focus was on the nonacademic, daily stressors and negative mood states of 152 students in medicine, business, divinity, graduate department of religion, and two graduate psychology departments. Additional comparisons were made between men and women, and married and single students. Study instruments included: the Hassles Scale, the Uplifts Scale, the Satisfaction Scale from the Flanagan Quality of Life Scale, the Anxiety and Depression Scales from Dupuy's General Well-Being Schedule, and the Positive Affect and Negative Affect Scales from the Oregon Quality of Life Questionnaire. Two departments reported significantly higher levels of negative mood: one of the psychology programs and the divinity school. Medical students reported the least negative mood. There were no departmental differences in daily stressors. Women reported more negative mood and more negative daily events than men, but they did not report fewer positive events or less global life satisfaction. There were no marital status differences. Overall, the level of negative mood was not high, and students reported a moderate but not extreme level of stress. (Author/SW)