Social workers in academic and agency settings have the opportunity to do funded research using the National Institutes of Health (NIH) R03 small grant mechanism designed for discrete, clearly defined projects that can be completed within a 1- to 2-year time period with limited funding. This article describes the R03 mechanism and provides a guide for the developmental steps in writing a successful grant application. It identifies the recent NIH program announcements titled "Research on Social Work Practice and Concepts in Health" as an extraordinary opportunity for social work researchers seeking R03 funding. The R03 is ideal for new researchers, and the experience of one of the authors illustrates the decision-making and skill-development processes involved in submitting a successful grant proposal.