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Brody, Gene H.; Chen, Yi-fu; Beach, Steven R. H. – Journal of Child Psychology and Psychiatry, 2013
Background: Randomized prevention trials provide a unique opportunity to test hypotheses about the interaction of genetic predispositions with contextual processes to create variations in phenotypes over time. Methods: Using two longitudinal, randomized prevention trials, molecular genetic and alcohol use outcome data were gathered from more than…
Descriptors: Prevention, Genetics, Drinking, At Risk Persons
Brody, Gene H.; Beach, Steven R. H.; Philibert, Robert A.; Chen, Yi-fu; Lei, Man-Kit; Murry, Velma McBride; Brown, Anita C. – Journal of Consulting and Clinical Psychology, 2009
The authors used a longitudinal, prospective design to investigate a moderation effect in the association between a genetic vulnerability factor, a variable nucleotide repeat polymorphism in the promoter region of "5HTT" (5-HTTLPR), and increases in youths' substance use. The primary study hypothesis predicted that involved-supportive…
Descriptors: Parenting Styles, Child Rearing, Adolescents, Genetics