There seems to be limited work addressing how depression is linked to elements of student functioning in the school setting other than academic achievement. This study investigated possible correlates of depressive symptoms with school engagement and disengagement. We examined four specific school variables (school motivation, intentions to quit, absence, and truancy) in a sample of 791 adolescents between 15 and 18 years of age in a Norwegian upper secondary vocational school. The results indicated that symptoms of depression could be a risk factor for school disengagement, and particularly for intentions to quit school. However, as only moderate associations were found, it appears that many depressed students manage to keep up their school engagement. This applied to both genders. However, the findings underline the importance of developing effective methods to identify and help depressed students who do have difficulty keeping up school engagement. Implications for practice are suggested.