There is clear and convincing evidence that students with disabilities living in poverty are facing the double jeopardy of dealing with issues associated with their disability, as well as the challenges of living in minimal conditions. Improving outcomes for this population requires the identification and implementation of effective programs. This study analyzed program factors and post-school outcomes of 500 former students with disabilities to determine to what extent predictions regarding employment for these students can be determined. Findings suggest that in high-relative poverty areas, participation in career technical education is associated with higher rates of employment during and after high school.