The use of recent college graduates as uncertified classroom teachers has increased in recent years, with the growth of Teach for America, alternative certification routes for teachers, and alternative schools for urban children placed at risk. Few studies to date have investigated the effects of using these inexperienced teachers on the quality of classroom instruction and student engagement in learning. This study examines the effectiveness of using uncertified teaching fellows in alternative urban middle schools that employ the NativityMiguel educational model. Results support the value of using such teachers, provided they are well prepared, mentored, and given appropriate teaching responsibilities as they become more proficient in the classroom. Implications for practice in urban schools are discussed.