This study reports results from a national Internet-based survey administered anonymously to a cross-section of social work faculty in the United States. Drawn from a sampling frame of 700 accredited or in candidacy schools, data were collected between November 2010 and March 2011. We investigate the role of sex, sexual orientation, race, religious affiliation and beliefs, religiosity, political ideology, sexism, and interest in sexuality/LGBTQ issues. Race, religiosity, political ideology, and sexism are associated with sexual prejudice, which was endorsed among a small percentage (14%) of the sample (n?=?303). Outcome scores were not statistically different based on the targets' sex. Strategies are recommended to reduce sexual prejudice among social work faculty and to increase institutional support for acceptance in the academy.