This educational newsletter highlights a lead article, "Evidence-Based Research in Education." The article explains that evidence-based research emerged in the field of medicine over 50 years ago, resulting in major advances in the treatment and prevention of disease. It adds that clinical guidelines and protocols are based on the results of controlled experiments following rigorous standards of science. The U.S. Department of Education is embracing evidence-based research to improve the effectiveness of educational interventions and, in turn, academic achievement. The article discusses the No Child Left Behind Act and the Coalition for Evidence-Based Policy. It recommends strategies for the Department of Education to bring evidence-driven progress to education. Other information materials in the newsletter are: "The What Works Clearinghouse"; "NDDR Grantees Review WWC Draft Standards"; and "Resolution of the AAMR on Evidence-Based Research and Intellectual Disability." (BT)