Across the nation grassroots efforts are springing up in which technical professionals are helping enhance science education. This guide has been prepared to help technical professionals become productively involved in enhancing K-12 science education. It has been prepared by scientists and engineers at Sandia National Laboratories who have been extensively involved in the K-12 science education effort for several years. This guide outlines key principles for conducting effective education outreach activities. Many of these principles are illustrated with examples of activities that proved successful in the Sandia program. This guide is divided into the following sections: (1) Introduction, (2) Science Education: Things You Need to Know Before Getting Involved, (3) Working Effectively With Students, (4) Working Effectively With Teachers, (4) Conducting a Tour of Your Worksite, (5) Sources of Hands-On Science and Math Activity Ideas, and (6) Reader Questionnaire. (JRH)