Intended as a guide for both novice and experienced researchers, this collection of articles focuses on single-subject experimental research used for investigations in literacy. The premise of the collection is that this single-subject approach allows researchers--both those from outside the classroom and teacher-researchers--to discover how an instructional intervention affects the student actually in need of assistance. The articles and their authors are: (1) "What Is Single-Subject Experimental Research?" (Sandra McCormick); (2) "Reversal Designs" (David B. Yaden, Jr.); (3) "Multiple-Baseline Designs" (James Kucera and Saul Axelrod); (4) "Alternating-Treatments Designs" (Susan B. Neuman); (5) "Statistical Analysis Procedures for Single-Subject Designs" (Michael L. Kamil); (6)"Combining Single-Subject Designs with Qualitative Research" (Tanja L. Bisesi and Taffy E. Raphael); (7) "Teachers Using Single-Subject Designs in the Classroom" (Judith A. Braithwaite); and (8) "Important Issues Related to Single-Subject Experimental Research" (Annemarie Sullivan Palincsar and Andrea DeBruin Parecki). Three appendixes conclude the collection: Appendix A--"Conventions for Displaying Data on Line Graphs" (Sandra McCormick); Appendix B--"Comparison of Research Methodologies Commonly Used in Literacy Investigations" (Sandra McCormick); and Appendix C--"Single-Subject Experimental Research Studies with Literacy-Related Themes" (Susan B. Neuman). (NKA)