This paper addresses the personological aspects relative to male and female success in two subject areas (math and science) and addresses specific concerns in the area of mentoring. Personality factors operative for success in math and science are reviewed, and teachers are advised to encourage, support, and facilitate those personality traits which appear to augur for success. One particular technique for encouraging females to pursue their interests is mentoring. The need of the mentor to nurture, encourage, and develop certain salient personality traits is emphasized. Reasons why bright individuals (both females and males) do not succeed are listed, such as lack of product orientation and capitalizing on the wrong abilities. Guidelines are presented for mentoring creatively gifted youth. Mentors are urged to guide their female protegees to be sensitive to the elements that enable females to succeed in a male-oriented society and in sometimes male-dominated fields. Mentors to gifted females should also acknowledge the pros and cons of pursuing careers in male-dominated fields. (Includes 20 references) (JDD)