This guide to kindergarten through 12th grade drug abuse prevention curricula and programs addresses the need for thorough training of all school personnel, including teachers, counselors, nurses, administrators, and school board members. The first chapter discusses what can realistically be expected of school-based substance abuse prevention programs. The second chapter discusses drug policies and procedures and their purposes and how to develop the policies and procedures. The third chapter defines drug prevention and intervention efforts which may be categorized as curricula, programs, or multi-element projects. Seventeen curricula, eight programs, and two multi-element projects are described. A table summarizes the characteristics of the curricula and programs. Methods of instruction included in the table are role play, audiovisual, peer/teenage models, outside resources, service projects, and cooperative or small groups. Content areas listed are drug information, decision making, refusal skills, counter advertising, self awareness, goal setting, awareness of others, assertiveness, career development, coping skills, class climate, and parent materials. The fourth chapter presents a case study of the Pajaro Valley Unified School District. The appendix includes a resource list of classroom materials, background material, and agencies and services. (ABL)