The 1988 Progress Report covers research activities of the five branches of the Center for Research for Mothers and Children of the National Institute of Child Health and Human Development. An introductory section briefly describes the Center, notes staff activities and Center sponsored conferences and workshops, and identifies highlights of activities of each of the Branches. A separate section is then given to each Branch's activities reported in terms of an overview, program activities, research highlights, and staff activities. The five branches are: the Genetics and Teratology Branch; the Pregnancy and Perinatology Branch; the Endocrinology, Nutrition and Growth Branch; the Mental Retardation and Developmental Disabilities Branch; and the Human Learning and Behavior Branch. Noted is a new Branch, the Pediatric, Adolescent, and Maternal AIDS Branch which is conducting research on Acquired Immune Deficiency Syndrome as it affects women and children. As an example, research highlights for the Mental Retardation Branch cover: genetics and genetic disorders; inborn errors of metabolism; prenatal diagnosis; exogenous and environmental factors; behavioral and biobehavioral factors; language and communication; treatment of behavior disorders; and adaptation in family, residential, vocational, and educational settings. Tables provide detail on the grants and contracts active during August, 1988. (DB)