Extensive guidelines for the development of a comprehensive school-based health clinic at the middle, junior, or senior high school levels are presented. School-based clinics usually provide the primary health care services needed by adolescents: health maintenance examinations and assessments; diagnosis and treatment of acute and chronic illnesses; first aid; laboratory tests; screening for sexually-transmitted diseases; immunizations; gynecological exams; family planning counseling and related services; and sports physicals, to name a few. Thirteen chapters provide information on program initiation, planning, definition of goals, information gathering, site selection, building community support, media relations, gaining school approval, clinic design, funding, budget preparation, staff selection, clinic evaluation, building positive relationships in the school and maintaining community support. Appendices include an extensive bibliography, an adolescent health fact sheet, a list of potential services, and samples of a parent survey, a consent form, job descriptions, and a school-health care provider contract. (LMI)