This curriculum guide is intended to prepare students for entry-level employment in the health care industry. The two-year program, designed to be used in high schools in New York City, will prepare students to assist in various health career settings such as doctors' offices, hospital clinics, and group practice facilities. The curriculum guide, which includes material for the two-year program, is divided into two one-year segments--medical assisting/general, and medical assisting/ophthalmic--and is intended to be taught two periods a day, five days a week. The five units of the first-year segment cover these topics: introduction, related sciences, office administration, diagnostic procedures, and therapeutic procedures, while the second year's program contains five units: introduction, related sciences, office maintenance, diagnostic procedures, and therapeutic procedures for the ophthalmic field. Each unit consists of performance objectives and tasks to meet the performance objectives, keyed to teaching content. Teaching content is presented in a three-column format: tasks, development of technical skills, and reinforcement of basic skills. In addition, the guide contains a supplement on implementing basic skills into the curriculum. The supplement indicates various teaching approaches that can be used for the reinforcement of basic skills in prevocational and vocational/technical education. The guide also contains a bibliography, sample lesson plan, and sample test questions. (KC)