This brief guide discusses ways to provide safe instruction and to minimize the risk of injury and potential liability in a laboratory environment. The three main concerns covered are: (1) the physical plant must be in compliance with the Occupational Safety and Health Administration (OSHA); (2) the physical facility should have all tools in good working condition and have written records of maintenance and inspection activities; and (3) the instructional program should present curriculum and lessons that are current and relevant to present-day industrial practices and standards. (EM)