Summaries of demonstration projects in registered nurse (RN) education in seven Southern schools are presented. The report on the Prairie View A & M University program focuses on issues addressed in establishing a program: avoiding previous program pitfalls, curricular adaptation, teaching strategies, and challenge (equivalency) policies. The George Mason University program report looks at faculty reactions and roles in program development. In the University of North Carolina at Greensboro program report, the construction of challenge examinations is featured, with the issue of professional socialization during the program also considered. A program to accommodate and optimize working and learning opportunities in a community hospital was the focus of the program at Northwestern State University of Louisiana, with clinical laboratories an important program element. At the Medical University of South Carolina, the program was developed around the working and learning experiences at the medical center hospital, and the curriculum and evaluation of the program are outlined. The University of Maryland at Baltimore project featured a rural outreach effort, in which local attitudes and relationships at the three sites were carefully nurtured. Urban outreach and a competency-based curriculum are outlined in the University of South Florida's program report. (MSE)