This report is the third of three volumes describing the results of the evaluation of the National Science Foundation (NSF) Local Course Improvement (LOCI) program. This volume describes 12 project case studies undertaken as part of that evaluation. Three projects were designed to increase individualization of college science teaching; two involved applications of computing aids in teaching; four involved the design of laboratory materials with two of these being inquiry; and three were attempts to update the content of science courses. The projects chosen for the case studies were determined in two different ways. Two projects were chosen on the basis of reporting successful outcomes. The remaining 10 projects were chosen without knowledge of the outcomes from over 100 projects to represent types of settings (universities, four-year colleges, and two-year colleges) and academic backgrounds for the project directors. These were chosen at random after being categorized by school and program. The case studies represent a synthesis of on-site visits and study for the project proposals, reports, and materials. (GS)