New federal desegregation guidelines have been written so that states are required to define the missions of their public colleges and universities in non-ethnic terms, to establish numerical goals for the desegregation of student enrollments statewide and in each institution, and to set goals for desegregation of faculty, administrators, and other employees, as well as board membership and board staffs. To help in this new definition process, guidelines are here provided which take into account educational factors of desegregation. The following sections are included: defining institutional missions; assignment of new programs; provision of resources for black institutions; unnecessary program duplication; and desegregation of student enrollment, faculty, administration, non-academic staff, and governing boards. To assure wise use of state funds, and to provide diverse programs for a changing student and teaching population, the guidelines should be applied with a degree of flexibility to design educational policies and practices that contribute to fair educational opportunity for everyone. (DC)