Research evidence on the potentials of health education for contributing to resolution of national health issues was reviewed. It is concluded that greater investments in health education on selected problems for selected populations would yield a better cost-benefit return than comparable investments in tertiary medical care. High priority groups for specific education changes can be identified, as well as the point of diminishing returns of expenditure, thus focusing and containing health education programs. Among the 36 specific recommendations drawn from the research evidence are a series of criteria for design of health education programs. A general recommendation for a major federal investment in health education research is outlined. (Author/JD)