ERIC Number: ED172462
Record Type: RIE
Publication Date: 1978
Reference Count: 0
Paternal Contribution to Down's Syndrome Dispels Maternal Myths.
Abroms, Kippy I.; Bennett, Joan W.
The paper refutes the long held belief that Down's syndrome is the result of maternal age and maternal etiology. The author cites new evidence which demonstrates that Trisomy-21 (the presence in the chromosome of an extra arcocentric chromosome resulting from non-disjunction), the major cause (95% of the cases) of Down's syndrome, can originate in the egg or the sperm. Maternal origin was indicated in 74% of the cases and paternal origin was indicated in the 26% of the cases reviewed in the paper. The author concludes with a study of 37 college texts dealing with exceptionality (published between 1970-1978) reviewed for etiological considerations of Down's syndrome. Among findings of the review was that of the 35 texts which mention Trisomy-21, 26 include information regarding maternal origin and maternal age dependency. (Author/PHR)
Publication Type: Reports - Research
Education Level: N/A
Authoring Institution: Tulane Univ., New Orleans, LA.
Note: This research was partially supported by a Bio-Medical Sciences Support Grant to Tulane University