Some of the problems that occur for researchers using the TICCIT computer assisted instructional system are described. The underlying learning strategy of the TICCIT system states that the student rather than the developer is best able to select the order of instructional frames. In order to successfully engage in research with the TICCIT system, students must be placed in a setting where learner control is expected of them and in which they can manifest learner control behavior. Successful TICCIT research also requires that the system be flexible enough to be adapted to a variety of research designs, and that the researcher plan in advance for efficient data reduction. (Author/STS)