The special problems faced by black, Mexican-American, Appalachian, and ethnic white minorities in college education, particularly in chemistry, are examined in the papers contained in this conference report. The most important problems for all groups are deficiencies in verbal and written English, mathematics, general science, and intellectual background. Such students typically lack self confidence, and many expect to fail in college. Obstacles to higher education include college selection procedures, competitive pressures, faculty attitudes, teaching styles, and examinations and grading practices. Suggestions for minimizing these disadvantages include the use of clearly stated behavioral objectives, the use of supportive remedial programs in English and mathematics, and the use of broader liberal education programs. Descriptions of innovative chemistry instruction for underprepared students in ten colleges are summarized in the report. Five specific recommendations summarizing the conclusions reached are appended. (AL)