This document lists the indigenous languages of North and South America, with the exception of the Eskimo-Aleut languages, the European-based Creoles, and languages which represent Post-Columbian intrusions. Section I consists of genetic classification of the languages included (948 language-level entries). Section II is an alphabetic list of all names included in the first section, with the addition of variant spellings and alternate names (3,730). The basic material incorporated into this work has been taken from the two volumes of the Languages of the World series devoted to American Indian languages, published as supplements to "Anthropological Linguistics." Additional information was taken from the "Encyclopedia Britannica" and other sources. Classifications by Greenberg, Hoijer, Mason, McQuown, Sapir, Tovar, and Trager were consulted. A description of the classification system followed appears in the Introduction. This volume is the first of a series of five language lists covering the world's languages and their dialects. The remaining four lists, "The Languages of Northern and Eastern Eurasia,""Indo-European and Other Languages of the Indo-European Historic Area," and "The Languages of Oceania," are forthcoming, to be published by the ERIC Clearinghouse for Linguistics in 1971. (AMM)