The rationale of the integrated experience approach to teaching botany at Purdue University is given and the history of the audio-tutorial course at Purdue and its present organization are described. A sample week's unit of study is given, including transcription of the tape, reproduction of printed materials and photographs of other materials used. The physical facilities used at Purdue are described with some suggestions for alternatives. A discussion of operational aspects includes guidelines for the preparation of tapes, films and other materials, as well as notes on scheduling, testing and grading. A brief account of the development of an audio-tutorial program for elementary school science is given, and applications of the method to secondary school science are suggested. Appendices include copies of orientation material distributed to students, sample record cards, instructions for staff, an account of student research projects including a sample problem write-up from a student, a discussion of problems and pitfalls, and a plan for an idealized learning center. (EB)