Blood serum uric acid and cholesterol levels in the blood were studied in relation to inner drive and external pressures of college students in the U.S.A. and in Sweden. Subjects for the study included 210 American and 78 Swedish male and female college students and 138 college football players. The blood chemicals were measured by Technicon analyzers. The Scholastic Aptitude Test measured the academic ability of the American students, and high school grade point average with that of the Swedes. The findings show evidence of a positive relationship between inner desire to achieve and serum uric acid level, and between external environmental pressures and cholesterol level. Among students in a highly competitive American college, a significant correlation was found to exist between students' serum uric acid levels and their grade point averages. This finding was not observed in Sweden where admission is more selective and academic pressures are less. Intercollegiate football players had higher serum uric acid and cholesterol levels during football season than in Spring training. Male science majors also had higher serum chemical levels than those with other college majors. (Author/JS)